Modeling Spinal Muscular Atrophy in Drosophila

Spinal Muscular Atrophy (SMA), a recessive hereditary neurodegenerative disease in humans, has been linked to mutations in the survival motor neuron (SMN) gene. SMA patients display early onset lethality coupled with motor neuron loss and skeletal muscle atrophy. We used Drosophila, which encodes a...

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Autori principali: Chang, Howard Chia-Hao, Dimlich, Douglas N., Yokokura, Takakazu, Mukherjee, Ashim, Kankel, Mark W., Sen, Anindya, Sridhar, Vasanthi, Fulga, Tudor A., Hart, Anne C., Van Vactor, David, Artavanis-Tsakonas, Spyros
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527655/
https://ncbi.nlm.nih.gov/pubmed/18791638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003209
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