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Modeling Spinal Muscular Atrophy in Drosophila

Spinal Muscular Atrophy (SMA), a recessive hereditary neurodegenerative disease in humans, has been linked to mutations in the survival motor neuron (SMN) gene. SMA patients display early onset lethality coupled with motor neuron loss and skeletal muscle atrophy. We used Drosophila, which encodes a...

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Detalhes bibliográficos
Main Authors: Chang, Howard Chia-Hao, Dimlich, Douglas N., Yokokura, Takakazu, Mukherjee, Ashim, Kankel, Mark W., Sen, Anindya, Sridhar, Vasanthi, Fulga, Tudor A., Hart, Anne C., Van Vactor, David, Artavanis-Tsakonas, Spyros
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527655/
https://ncbi.nlm.nih.gov/pubmed/18791638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003209
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