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Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy

The clinical severity of the neurodegenerative disorder spinal muscular atrophy (SMA) is dependent on the levels of functional Survival Motor Neuron (SMN) protein. Consequently, current strategies for developing treatments for SMA generally focus on augmenting SMN levels. To identify additional pote...

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מידע ביבליוגרפי
Main Authors: Sen, Anindya, Dimlich, Douglas N., Guruharsha, K. G., Kankel, Mark W., Hori, Kazuya, Yokokura, Takakazu, Brachat, Sophie, Richardson, Delwood, Loureiro, Joseph, Sivasankaran, Rajeev, Curtis, Daniel, Davidow, Lance S., Rubin, Lee L., Hart, Anne C., Van Vactor, David, Artavanis-Tsakonas, Spyros
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696827/
https://ncbi.nlm.nih.gov/pubmed/23757500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301738110
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