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The Notch signalling system: recent insights into the complexity of a conserved pathway

Notch signalling links the fate of one cell to that of an immediate neighbour and consequently controls differentiation, proliferation and apoptotic events in multiple metazoan tissues. Perturbations in this pathway activity have been linked to several human genetic disorders and cancers. Recent gen...

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Vydáno v:Nat Rev Genet
Hlavní autoři: Guruharsha, K. G., Kankel, Mark W., Artavanis-Tsakonas, Spyros
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369923/
https://ncbi.nlm.nih.gov/pubmed/22868267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3272
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