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The Notch signalling system: recent insights into the complexity of a conserved pathway

Notch signalling links the fate of one cell to that of an immediate neighbour and consequently controls differentiation, proliferation and apoptotic events in multiple metazoan tissues. Perturbations in this pathway activity have been linked to several human genetic disorders and cancers. Recent gen...

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Bibliografski detalji
Izdano u:Nat Rev Genet
Glavni autori: Guruharsha, K. G., Kankel, Mark W., Artavanis-Tsakonas, Spyros
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369923/
https://ncbi.nlm.nih.gov/pubmed/22868267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3272
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