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The Notch signalling system: recent insights into the complexity of a conserved pathway
Notch signalling links the fate of one cell to that of an immediate neighbour and consequently controls differentiation, proliferation and apoptotic events in multiple metazoan tissues. Perturbations in this pathway activity have been linked to several human genetic disorders and cancers. Recent gen...
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| 發表在: | Nat Rev Genet |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369923/ https://ncbi.nlm.nih.gov/pubmed/22868267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3272 |
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