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Modeling spinal muscular atrophy in Drosophila links Smn to FGF signaling
Spinal muscular atrophy (SMA), a devastating neurodegenerative disorder characterized by motor neuron loss and muscle atrophy, has been linked to mutations in the Survival Motor Neuron (SMN) gene. Based on an SMA model we developed in Drosophila, which displays features that are analogous to the hum...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101100/ https://ncbi.nlm.nih.gov/pubmed/21300852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004016 |
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