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The 26S proteasome drives trinucleotide repeat expansions
Trinucleotide repeat (TNR) expansion is the causative mutation for at least 17 inherited neurological diseases. An important question in the field is which proteins drive the expansion process. This study reports that the multi-functional protein Sem1 is a novel driver of TNR expansions in budding y...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3695522/ https://ncbi.nlm.nih.gov/pubmed/23620289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt295 |
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