Stabilizing Effects of Interruptions on Trinucleotide Repeat Expansions in Saccharomyces cerevisiae

In most trinucleotide repeat (TNR) diseases, the primary factor determining the likelihood of expansions is the length of the TNR. In some diseases, however, stable alleles contain one to three base pair substitutions that interrupt the TNR tract. The unexpected stability of these alleles compared t...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Rolfsmeier, Michael L., Lahue, Robert S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85072/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10594019/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.1.173-180.2000
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