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Stabilizing Effects of Interruptions on Trinucleotide Repeat Expansions in Saccharomyces cerevisiae

In most trinucleotide repeat (TNR) diseases, the primary factor determining the likelihood of expansions is the length of the TNR. In some diseases, however, stable alleles contain one to three base pair substitutions that interrupt the TNR tract. The unexpected stability of these alleles compared t...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Rolfsmeier, Michael L., Lahue, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2000
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85072/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10594019/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.1.173-180.2000
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