Stabilizing Effects of Interruptions on Trinucleotide Repeat Expansions in Saccharomyces cerevisiae

In most trinucleotide repeat (TNR) diseases, the primary factor determining the likelihood of expansions is the length of the TNR. In some diseases, however, stable alleles contain one to three base pair substitutions that interrupt the TNR tract. The unexpected stability of these alleles compared t...

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Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Rolfsmeier, Michael L., Lahue, Robert S.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 2000
Предметы:	DNA Dynamics and Chromosome Structure
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85072/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10594019/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.1.173-180.2000
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