Trinucleotide repeat expansions catalyzed by human cell-free extracts

Trinucleotide repeat expansions cause 17 heritable human neurological disorders. In some diseases, somatic expansions occur in non-proliferating tissues such as brain where DNA replication is limited. This finding stimulated significant interest in replication-independent expansion mechanisms. Aberr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Stevens, Jennifer R, Lahue, Elaine E, Li, Guo-Min, Lahue, Robert S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2013
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616437/
https://ncbi.nlm.nih.gov/pubmed/23337586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.12
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