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Replication and Expansion of Trinucleotide Repeats in Yeast

The mechanisms of trinucleotide repeat expansions, underlying more than a dozen hereditary neurological disorders, are yet to be understood. Here we looked at the replication of (CGG)(n) · (CCG)(n) and (CAG)(n) · (CTG)(n) repeats and their propensity to expand in Saccharomyces cerevisiae. Using elec...

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Detalhes bibliográficos
Main Authors: Pelletier, Richard, Krasilnikova, Maria M., Samadashwily, George M., Lahue, Robert, Mirkin, Sergei M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141142/
https://ncbi.nlm.nih.gov/pubmed/12556494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1349-1357.2003
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