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Stability of the Human Fragile X (CGG)(n) Triplet Repeat Array in Saccharomyces cerevisiae Deficient in Aspects of DNA Metabolism
Expanded trinucleotide repeats underlie a growing number of human diseases. The human FMR1 (CGG)(n) array can exhibit genetic instability characterized by progressive expansion over several generations leading to gene silencing and the development of the fragile X syndrome. While expansion is depend...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC84419/ https://ncbi.nlm.nih.gov/pubmed/10409756 |
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