Stability of the Human Fragile X (CGG)(n) Triplet Repeat Array in Saccharomyces cerevisiae Deficient in Aspects of DNA Metabolism
Expanded trinucleotide repeats underlie a growing number of human diseases. The human FMR1 (CGG)(n) array can exhibit genetic instability characterized by progressive expansion over several generations leading to gene silencing and the development of the fragile X syndrome. While expansion is depend...
में बचाया:
| में प्रकाशित: | Mol Cell Biol |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Taylor & Francis
1999
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84419/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10409756/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.8.5675 |
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