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A weighted sampling algorithm for the design of RNA sequences with targeted secondary structure and nucleotide distribution
Motivations: The design of RNA sequences folding into predefined secondary structures is a milestone for many synthetic biology and gene therapy studies. Most of the current software uses similar local search strategies (i.e. a random seed is progressively adapted to acquire the desired folding prop...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694657/ https://ncbi.nlm.nih.gov/pubmed/23812999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt217 |
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