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A weighted sampling algorithm for the design of RNA sequences with targeted secondary structure and nucleotide distribution

Motivations: The design of RNA sequences folding into predefined secondary structures is a milestone for many synthetic biology and gene therapy studies. Most of the current software uses similar local search strategies (i.e. a random seed is progressively adapted to acquire the desired folding prop...

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Hlavní autoři: Reinharz, Vladimir, Ponty, Yann, Waldispühl, Jérôme
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694657/
https://ncbi.nlm.nih.gov/pubmed/23812999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt217
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