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Poly(A) motif prediction using spectral latent features from human DNA sequences

Motivation: Polyadenylation is the addition of a poly(A) tail to an RNA molecule. Identifying DNA sequence motifs that signal the addition of poly(A) tails is essential to improved genome annotation and better understanding of the regulatory mechanisms and stability of mRNA. Existing poly(A) motif p...

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Bibliographic Details
Main Authors: Xie, Bo, Jankovic, Boris R., Bajic, Vladimir B., Song, Le, Gao, Xin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694652/
https://ncbi.nlm.nih.gov/pubmed/23813000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt218
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