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Haplotype assembly in polyploid genomes and identical by descent shared tracts

Motivation: Genome-wide haplotype reconstruction from sequence data, or haplotype assembly, is at the center of major challenges in molecular biology and life sciences. For complex eukaryotic organisms like humans, the genome is vast and the population samples are growing so rapidly that algorithms...

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Autori principali: Aguiar, Derek, Istrail, Sorin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694639/
https://ncbi.nlm.nih.gov/pubmed/23813004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt213
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