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Combining structure probing data on RNA mutants with evolutionary information reveals RNA-binding interfaces
Systematic structure probing experiments (e.g. SHAPE) of RNA mutants such as the mutate-and-map (MaM) protocol give us a direct access into the genetic robustness of ncRNA structures. Comparative studies of homologous sequences provide a distinct, yet complementary, approach to analyze structural an...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914100/ https://ncbi.nlm.nih.gov/pubmed/27095200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw217 |
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