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Towards 3D structure prediction of large RNA molecules: an integer programming framework to insert local 3D motifs in RNA secondary structure

Motivation: The prediction of RNA 3D structures from its sequence only is a milestone to RNA function analysis and prediction. In recent years, many methods addressed this challenge, ranging from cycle decomposition and fragment assembly to molecular dynamics simulations. However, their predictions...

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Detalhes bibliográficos
Main Authors: Reinharz, Vladimir, Major, François, Waldispühl, Jérôme
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371858/
https://ncbi.nlm.nih.gov/pubmed/22689763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts226
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