A truncated splice-variant of the FcεRIβ receptor subunit is critical for microtubule formation and degranulation in mast cells

Human linkage analyses have implicated the MS4A2-containing gene locus (encoding FcεRIβ) as a candidate for allergy susceptibility. We have identified a truncation of FcεRIβ (t-FcεRIβ) in humans which contains a putative calmodulin binding domain and thus, we sought to identify the role of this vari...

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Detaylı Bibliyografya
Asıl Yazarlar: Cruse, Glenn, Beaven, Michael A., Ashmole, Ian, Bradding, Peter, Gilfillan, Alasdair M., Metcalfe, Dean D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694348/
https://ncbi.nlm.nih.gov/pubmed/23643722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.04.007
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