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A truncated splice-variant of the FcεRIβ receptor subunit is critical for microtubule formation and degranulation in mast cells
Human linkage analyses have implicated the MS4A2-containing gene locus (encoding FcεRIβ) as a candidate for allergy susceptibility. We have identified a truncation of FcεRIβ (t-FcεRIβ) in humans which contains a putative calmodulin binding domain and thus, we sought to identify the role of this vari...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694348/ https://ncbi.nlm.nih.gov/pubmed/23643722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.04.007 |
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