Abnormal accumulation and recycling of glycoproteins visualized in Niemann–Pick type C cells using the chemical reporter strategy

Niemann–Pick type C (NPC) disease is characterized by impaired cholesterol efflux from late endosomes and lysosomes and secondary accumulation of lipids. Although impaired trafficking of individual glycoproteins and glycolipids has been noted in NPC cells and other storage disorders, there is curren...

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Detaylı Bibliyografya
Asıl Yazarlar: Mbua, Ngalle Eric, Flanagan-Steet, Heather, Johnson, Steven, Wolfert, Margreet A., Boons, Geert-Jan, Steet, Richard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690855/
https://ncbi.nlm.nih.gov/pubmed/23733943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221105110
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