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Strain-Promoted Alkyne-Azide Cycloadditions (SPAAC) Reveal New Features of Glycoconjugate Biosynthesis

We have shown that 4-Dibenzocyclooctynol (DIBO), which can easily be obtained by a streamlined synthetic approach, reacts exceptionally fast in the absence of a Cu(I) catalyst with azido-containing compounds to give stable triazoles. Chemical modifications of DIBO, such as oxidation of the alcohol t...

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Detalles Bibliográficos
Main Authors: Mbua, Ngalle Eric, Guo, Jun, Wolfert, Margreet A., Steet, Richard, Boons, Geert-Jan
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151320/
https://ncbi.nlm.nih.gov/pubmed/21661087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201100117
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