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Polar Dibenzocyclooctynes for Selective Labeling of Extracellular Glycoconjugates of Living Cells

Although strain-promoted alkyne-azide cycloadditions (SPAAC) have found wide utility in biological and material sciences, the low polarity and limited water solubility of commonly used cyclooctynes represents a serious shortcoming. To address this problem, an efficient synthetic route has been devel...

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Detalhes bibliográficos
Main Authors: Friscourt, Frédéric, Ledin, Petr A., Mbua, Ngalle Eric, Flanagan-Steet, Heather R., Wolfert, Margreet A., Steet, Richard, Boons, Geert-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319718/
https://ncbi.nlm.nih.gov/pubmed/22376061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3002666
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