Selective Labeling of Living Cells by a Photo-Triggered Click Reaction

Photo-triggering of the metal-free azide to acetylene cycloaddition reaction was achieved by masking the triple bond of dibenzocyclooctynes as cyclopropenone. Such masked cyclooctynes do not react with azides in the dark. Irradiation of cyclopropenones results in the efficient (Φ(355) = 0.33) and cl...

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Bibliographic Details
Main Authors: Poloukhtine, Andrei A., Mbua, Ngalle Eric, Wolfert, Margreet A., Boons, Geert-Jan, Popik, Vladimir V.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776736/
https://ncbi.nlm.nih.gov/pubmed/19860481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9054096
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