A carregar...

ARF6-Mediated Endosome Recycling Reverses Lipid Accumulation Defects in Niemann-Pick Type C Disease

In human Niemann-Pick Type C (NPC) disease, endosomal trafficking defects lead to an accumulation of free cholesterol and other lipids in late endosome/lysosome (LE/LY) compartments, a subsequent block in cholesterol esterification and significantly reduced cholesterol efflux out of the cell. Here w...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schweitzer, Jill Kuglin, Pietrini, Sean D., D'Souza-Schorey, Crislyn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664925/
https://ncbi.nlm.nih.gov/pubmed/19365558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005193
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!