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Diminished Autophagy Limits Cardiac Injury in Mouse Models of Type 1 Diabetes
Cardiac autophagy is inhibited in type 1 diabetes. However, it remains unknown if the reduced autophagy contributes to the pathogenesis of diabetic cardiomyopathy. We addressed this question using mouse models with gain- and loss-of-autophagy. Autophagic flux was inhibited in diabetic hearts when me...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689952/ https://ncbi.nlm.nih.gov/pubmed/23658055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.474650 |
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