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Suppression of autophagy is protective in high glucose-induced cardiomyocyte injury

Hyperglycemia is linked to increased heart failure among diabetic patients. However, the mechanisms that mediate hyperglycemia-induced cardiac damage remain poorly understood. Autophagy is a cellular degradation pathway that plays important roles in cellular homeostasis. Autophagic activity is alter...

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Bibliographic Details
Main Authors: Kobayashi, Satoru, Xu, Xianmin, Chen, Kai, Liang, Qiangrong
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405845/
https://ncbi.nlm.nih.gov/pubmed/22498478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.18980
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