Enhanced autophagy ameliorates cardiac proteinopathy

Basal autophagy is a crucial mechanism in cellular homeostasis, underlying both normal cellular recycling and the clearance of damaged or misfolded proteins, organelles and aggregates. We showed here that enhanced levels of autophagy induced by either autophagic gene overexpression or voluntary exer...

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Bibliographische Detailangaben
Hauptverfasser: Bhuiyan, Md. Shenuarin, Pattison, J. Scott, Osinska, Hanna, James, Jeanne, Gulick, James, McLendon, Patrick M., Hill, Joseph A., Sadoshima, Junichi, Robbins, Jeffrey
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859422/
https://ncbi.nlm.nih.gov/pubmed/24177425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70877
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