Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

Hedgehog signalling—an essential pathway during embryonic pancreatic development, the misregulation of which has been implicated in several forms of cancer—may also be an important mediator in human pancreatic carcinoma(1–8). Here we report that sonic hedgehog, a secreted hedgehog ligand, is abnorma...

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Autors principals: Thayer, Sarah P., Pasca di Magliano, Marina, Heiser, Patrick W., Nielsen, Corinne M., Roberts, Drucilla J., Lauwers, Gregory Y., Ping Qi, Yan, Gysin, Stephan, Fernández-del Castillo, Carlos, Yajnik, Vijay, Antoniu, Bozena, McMahon, Martin, Warshaw, Andrew L., Hebrok, Matthias
Format: Artigo
Idioma:Inglês
Publicat: 2003
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688051/
https://ncbi.nlm.nih.gov/pubmed/14520413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature02009
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