Nestin Mediates Hedgehog Pathway Tumorigenesis

The intermediate filament protein Nestin serves as a biomarker for stem cells and has been used to identify subsets of cancer stem-like cells. However, the mechanistic contributions of Nestin to cancer pathogenesis are not understood. Here we report that Nestin binds the hedgehog pathway transcripti...

Full description

Saved in:
Bibliographic Details
Published in:Cancer Res
Main Authors: Li, Peng, Lee, Eric, Du, Fang, Gordon, Renata E., Yuelling, Larra W., Liu, Yongqiang, Ng, Jessica M.Y., Zhang, Hao, Wu, Jinhua, Korshunov, Andrey, Pfister, Stefan, Curran, Tom, Yang, Zeng-jie
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091083/
https://ncbi.nlm.nih.gov/pubmed/27496710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1547
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items