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Nestin Mediates Hedgehog Pathway Tumorigenesis

The intermediate filament protein Nestin serves as a biomarker for stem cells and has been used to identify subsets of cancer stem-like cells. However, the mechanistic contributions of Nestin to cancer pathogenesis are not understood. Here we report that Nestin binds the hedgehog pathway transcripti...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Li, Peng, Lee, Eric, Du, Fang, Gordon, Renata E., Yuelling, Larra W., Liu, Yongqiang, Ng, Jessica M.Y., Zhang, Hao, Wu, Jinhua, Korshunov, Andrey, Pfister, Stefan, Curran, Tom, Yang, Zeng-jie
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091083/
https://ncbi.nlm.nih.gov/pubmed/27496710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1547
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