Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

Hedgehog signalling—an essential pathway during embryonic pancreatic development, the misregulation of which has been implicated in several forms of cancer—may also be an important mediator in human pancreatic carcinoma(1–8). Here we report that sonic hedgehog, a secreted hedgehog ligand, is abnorma...

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Hlavní autoři: Thayer, Sarah P., Pasca di Magliano, Marina, Heiser, Patrick W., Nielsen, Corinne M., Roberts, Drucilla J., Lauwers, Gregory Y., Ping Qi, Yan, Gysin, Stephan, Fernández-del Castillo, Carlos, Yajnik, Vijay, Antoniu, Bozena, McMahon, Martin, Warshaw, Andrew L., Hebrok, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688051/
https://ncbi.nlm.nih.gov/pubmed/14520413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature02009
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