Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis

Many genes initially identified for their roles in cell fate determination or signaling during development can have a significant impact on tumorigenesis. In the developing cerebellum, Sonic hedgehog (Shh) stimulates the proliferation of granule neuron precursor cells (GNPs) by activating the Gli tr...

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Bibliografiske detaljer
Main Authors: Lee, Eunice Y., Ji, Hongkai, Ouyang, Zhengqing, Zhou, Baiyu, Ma, Wenxiu, Vokes, Steven A., McMahon, Andrew P., Wong, Wing H., Scott, Matthew P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906878/
https://ncbi.nlm.nih.gov/pubmed/20460306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004602107
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