Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis

Activation of sonic hedgehog (Shh) signaling occurs in the majority of pancreatic ductal adenocarcinomas. Here we investigate the mechanisms by which Shh contributes to pancreatic tumorigenesis. We find that Shh expression enhances proliferation of pancreatic duct epithelial cells, potentially throu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Morton, Jennifer P., Mongeau, Michelle E., Klimstra, David S., Morris, John P., Lee, Yie Chia, Kawaguchi, Yoshiya, Wright, Christopher V. E., Hebrok, Matthias, Lewis, Brian C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2007
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828712/
https://ncbi.nlm.nih.gov/pubmed/17372229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701158104
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia