A carregar...

KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is characterized by near-universal mutations in KRAS and frequent deregulation of crucial embryonic signalling pathways, including the Hedgehog (Hh) and Wnt–β-catenin cascades. The creation of mouse models that closely resemble the human disease has provided a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Morris, John P., Wang, Sam C., Hebrok, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085546/
https://ncbi.nlm.nih.gov/pubmed/20814421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2899
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!