Positive Crosstalk Between Hedgehog and NF-κB Pathways Is Dependent on KRAS Mutation in Pancreatic Ductal Adenocarcinoma

It has been shown that aberrant activation of the Hedgehog (Hh) and nuclear factor-kappa B (NF-κB) signaling pathways plays an important role in the pancreatic carcinogenesis, and KRAS mutation is a hallmark of pancreatic ductal adenocarcinoma (PDAC). Until now, the role of KRAS mutation in the cont...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Wang, Yuqiong, Wang, Dan, Dai, Yanmiao, Kong, Xiangyu, Zhu, Xian, Fan, Yunxia, Wang, Yaodong, Wu, Hongyu, Jin, Jing, Yao, Wenzhu, Gao, Jun, Wang, Kaixuan, Xu, Hongwei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144522/
https://ncbi.nlm.nih.gov/pubmed/34046348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.652283
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