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Notochord repression of endodermal Sonic hedgehog permits pancreas development

Notochord signals to the endoderm are required for development of the chick dorsal pancreas. Sonic hedgehog (SHH) is normally absent from pancreatic endoderm, and we provide evidence that notochord, in contrast to its effects on adjacent neuroectoderm where SHH expression is induced, represses SHH e...

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Hlavní autoři: Hebrok, Matthias, Kim, Seung K., Melton, Douglas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC316875/
https://ncbi.nlm.nih.gov/pubmed/9620856
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