Notochord repression of endodermal Sonic hedgehog permits pancreas development

Notochord signals to the endoderm are required for development of the chick dorsal pancreas. Sonic hedgehog (SHH) is normally absent from pancreatic endoderm, and we provide evidence that notochord, in contrast to its effects on adjacent neuroectoderm where SHH expression is induced, represses SHH e...

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Номзүйн дэлгэрэнгүй

-д хэвлэсэн:	Genes Dev
Үндсэн зохиолчид:	Hebrok, Matthias, Kim, Seung K., Melton, Douglas A.
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Cold Spring Harbor Laboratory Press 1998
Нөхцлүүд:	Research Paper
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316875/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9620856/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.11.1705
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