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Role of urea in intestinal barrier dysfunction and disruption of epithelial tight junction in CKD

BACKGROUND: Chronic kidney disease (CKD) impairs intestinal barrier function which leads to endotoxemia and systemic inflammation. We have found depletion of intestinal epithelial tight junction (TJ) proteins in animals with CKD. We further showed that addition of ESRD patients' plasma to the c...

詳細記述

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書誌詳細
主要な著者: Vaziri, Nosratola D., Yuan, Jun, Norris, Keith
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686571/
https://ncbi.nlm.nih.gov/pubmed/23258127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000345969
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