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Role of urea in intestinal barrier dysfunction and disruption of epithelial tight junction in CKD
BACKGROUND: Chronic kidney disease (CKD) impairs intestinal barrier function which leads to endotoxemia and systemic inflammation. We have found depletion of intestinal epithelial tight junction (TJ) proteins in animals with CKD. We further showed that addition of ESRD patients' plasma to the c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3686571/ https://ncbi.nlm.nih.gov/pubmed/23258127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000345969 |
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