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Uremic plasma impairs barrier function and depletes the tight junction protein constituents of intestinal epithelium
BACK GROUND: CKD causes intestinal barrier dysfunction which by allowing influx of endotoxin and other noxious products contributes to the CKD-associated systemic inflammation and uremic toxicity. We have recently shown that intestinal barrier dysfunction in CKD animals is due to degradation of tran...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725306/ https://ncbi.nlm.nih.gov/pubmed/23128155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000343886 |
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