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Uremic plasma impairs barrier function and depletes the tight junction protein constituents of intestinal epithelium

BACK GROUND: CKD causes intestinal barrier dysfunction which by allowing influx of endotoxin and other noxious products contributes to the CKD-associated systemic inflammation and uremic toxicity. We have recently shown that intestinal barrier dysfunction in CKD animals is due to degradation of tran...

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Autors principals: Vaziri, Nosratola D., Goshtasbi, Nisa, Yuan, Jun, Jellbauer, Stefan, Moradi, Hamid, Raffatellu, Manuela, Kalantar-Zadeh, Kamyar
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725306/
https://ncbi.nlm.nih.gov/pubmed/23128155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000343886
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