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Oral activated charcoal adsorbent (AST-120) ameliorates CKD-induced intestinal epithelial barrier disruption

BACK GROUND: CKD impairs intestinal barrier function which by allowing influx of noxious products causes systemic inflammation. We have recently shown that intestinal barrier dysfunction in CKD is due to degradation of epithelial tight junction (TJ) which is, in part, mediated by influx of urea and...

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Autors principals: Vaziri, Nosratola D., Yuan, Jun, Khazaeli, Mahyar, Masuda, Yuichi, Ichii, Hirohito, Liu, Shuman
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777856/
https://ncbi.nlm.nih.gov/pubmed/23689670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000351171
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