LCZ696 (Sacubitril/valsartan) ameliorates oxidative stress, inflammation, fibrosis and improves renal function beyond angiotensin receptor blockade in CKD

Progressive deterioration of kidney function in chronic kidney disease (CKD) is mediated by hypertension, oxidative stress, inflammation, and fibrosis. Renin-angiotensin blockade is commonly used to retard CKD progression. In addition, vasoactive peptides have been shown to reduce blood pressure and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Transl Res
Päätekijät: Jing, Wanghui, Vaziri, Nosratola D, Nunes, Ane, Suematsu, Yasunori, Farzaneh, Ted, Khazaeli, Mahyar, Moradi, Hamid
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: e-Century Publishing Corporation 2017
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752897/
https://ncbi.nlm.nih.gov/pubmed/29312499
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