LCZ696 (Sacubitril/valsartan) ameliorates oxidative stress, inflammation, fibrosis and improves renal function beyond angiotensin receptor blockade in CKD

Progressive deterioration of kidney function in chronic kidney disease (CKD) is mediated by hypertension, oxidative stress, inflammation, and fibrosis. Renin-angiotensin blockade is commonly used to retard CKD progression. In addition, vasoactive peptides have been shown to reduce blood pressure and...

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Podrobná bibliografie
Vydáno v:Am J Transl Res
Hlavní autoři: Jing, Wanghui, Vaziri, Nosratola D, Nunes, Ane, Suematsu, Yasunori, Farzaneh, Ted, Khazaeli, Mahyar, Moradi, Hamid
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752897/
https://ncbi.nlm.nih.gov/pubmed/29312499
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