Oral activated charcoal adsorbent (AST-120) ameliorates CKD-induced intestinal epithelial barrier disruption

BACK GROUND: CKD impairs intestinal barrier function which by allowing influx of noxious products causes systemic inflammation. We have recently shown that intestinal barrier dysfunction in CKD is due to degradation of epithelial tight junction (TJ) which is, in part, mediated by influx of urea and...

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Hlavní autoři: Vaziri, Nosratola D., Yuan, Jun, Khazaeli, Mahyar, Masuda, Yuichi, Ichii, Hirohito, Liu, Shuman
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777856/
https://ncbi.nlm.nih.gov/pubmed/23689670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000351171
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