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Role of urea in intestinal barrier dysfunction and disruption of epithelial tight junction in CKD

BACKGROUND: Chronic kidney disease (CKD) impairs intestinal barrier function which leads to endotoxemia and systemic inflammation. We have found depletion of intestinal epithelial tight junction (TJ) proteins in animals with CKD. We further showed that addition of ESRD patients' plasma to the c...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Vaziri, Nosratola D., Yuan, Jun, Norris, Keith
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686571/
https://ncbi.nlm.nih.gov/pubmed/23258127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000345969
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