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Biological effects of simple changes in functionality on rhodium metalloinsertors

DNA mismatch repair (MMR) is crucial to ensuring the fidelity of the genome. The inability to correct single base mismatches leads to elevated mutation rates and carcinogenesis. Using metalloinsertors–bulky metal complexes that bind with high specificity to mismatched sites in the DNA duplex–our lab...

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書誌詳細
主要な著者: Weidmann, Alyson G., Komor, Alexis C., Barton, Jacqueline K.
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society Publishing 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685451/
https://ncbi.nlm.nih.gov/pubmed/23776288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsta.2012.0117
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