β-Arrestin-Selective G Protein-Coupled Receptor Agonists Engender Unique Biological Efficacy in Vivo

Biased G protein-coupled receptor agonists are orthosteric ligands that possess pathway-selective efficacy, activating or inhibiting only a subset of the signaling repertoire of their cognate receptors. In vitro, d-Trp(12),Tyr(34)-bPTH(7–34) [bPTH(7–34)], a biased agonist for the type 1 PTH receptor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gesty-Palmer, Diane, Yuan, Ling, Martin, Bronwen, Wood, William H., Lee, Mi-Hye, Janech, Michael G., Tsoi, Lam C., Zheng, W. Jim, Luttrell, Louis M., Maudsley, Stuart
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Endocrine Society 2013
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683806/
https://ncbi.nlm.nih.gov/pubmed/23315939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1091
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak