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The Origins of Diversity and Specificity in G Protein-Coupled Receptor Signaling
The modulation of transmembrane signaling by G protein-coupled receptors (GPCRs) constitutes the single most important therapeutic target in medicine. Drugs acting on GPCRs have traditionally been classified as agonists, partial agonists, or antagonists based on a two-state model of receptor functio...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2656918/ https://ncbi.nlm.nih.gov/pubmed/15805429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.105.083121 |
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