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Allosteric Modulators of G Protein-Coupled Receptors: Future Therapeutics for Complex Physiological Disorders

G protein-coupled receptors (GPCRs) are one of the most important classes of proteins in the genome, not only because of their tremendous molecular diversity but because they are the targets of nearly 50% of current pharmacotherapeutics. The majority of these drugs affect GPCR activity by binding to...

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Detalhes bibliográficos
Main Authors: Wang, Liyun, Martin, Bronwen, Brenneman, Randall, Luttrell, Louis M., Maudsley, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775272/
https://ncbi.nlm.nih.gov/pubmed/19667132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.156380
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