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β-Arrestin-Selective G Protein-Coupled Receptor Agonists Engender Unique Biological Efficacy in Vivo
Biased G protein-coupled receptor agonists are orthosteric ligands that possess pathway-selective efficacy, activating or inhibiting only a subset of the signaling repertoire of their cognate receptors. In vitro, d-Trp(12),Tyr(34)-bPTH(7–34) [bPTH(7–34)], a biased agonist for the type 1 PTH receptor...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Endocrine Society
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683806/ https://ncbi.nlm.nih.gov/pubmed/23315939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1091 |
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